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HelpTest Code 10INT Factor X Inhibitor Profile, Technical Interpretation
Specimen Required
Only orderable as part of a profile. For more information see 10INE / Factor X Inhibitor Evaluation, Plasma.
Secondary ID
607440Useful For
Technical interpretation of inhibitor to coagulation factor X testing
Method Name
Only orderable as part of a profile. For more information see 10INE / Factor X Inhibitor Evaluation, Plasma.
Technical Interpretation
Reporting Name
FX Inhib Profile Tech InterpSpecimen Type
Plasma Na CitSpecimen Stability Information
| Specimen Type | Temperature | Time | Special Container |
|---|---|---|---|
| Plasma Na Cit | Frozen | 14 days |
Reject Due To
| Gross hemolysis | Reject |
| Gross lipemia | Reject |
| Gross icterus | Reject |
Clinical Information
Coagulation factor inhibitors arise in patients who are congenitally deficient in a specific factor in response to factor replacement therapy or they can either occur spontaneously without known cause or in response to a variety of medical conditions, including the postpartum state, immunologic disorders, certain antibiotic therapies, some malignancies, and advanced age.
Inhibitors of factor VIII coagulant activity are the most commonly occurring of the specific factor inhibitors.
Reference Values
Only orderable as part of a profile. For more information see 10INE / Factor X Inhibitor Evaluation, Plasma.
An interpretive report will be provided.
Interpretation
When testing is complete, if factor activity results fall within clinically normal ranges, an interpretive comment will be provided noting that inhibitor testing was not indicated and, therefore, not performed. If factor activity indicates the performance of inhibitor screen testing, an interpretive comment will be provided noting the presence or absence of a factor X inhibitor.
Cautions
Occasionally, a potent lupus-like anticoagulant may cause false-positive testing for a specific factor inhibitor (eg, factor VIII or IX).
Clinical Reference
1. Hoffman R, Benz Jr EJ, Silberstein LE, et al, eds. Hematology: Basic Principles and Practice. 7th ed. Elsevier; 2018
2. Kasper CK. Treatment of factor VIII inhibitors. Prog Hemost Thromb. 1989;9:57-86
Method Description
If the factor X activity level is normal or elevated, a computer-generated interpretive comment indicating inhibitor testing was not indicated and was not performed will be provided.
Day(s) Performed
Monday through FridayReport Available
3 to 5 daysSpecimen Retention Time
7 daysPerforming Laboratory
Mayo Clinic Laboratories in Rochester
Test Classification
Not ApplicableCPT Code Information
85390
LOINC Code Information
| Test ID | Test Order Name | Order LOINC Value |
|---|---|---|
| 10INT | FX Inhib Profile Tech Interp | 69049-5 |
| Result ID | Test Result Name | Result LOINC Value |
|---|---|---|
| 10INT | FX Inhib Profile Tech Interp | 69049-5 |