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Test Code 2AINH Factor II Inhibitor Profile, Professional Interpretation


Specimen Required


 


Secondary ID

607445

Useful For

Interpretation of testing for the detection and quantitation of inhibitor to factor II

Method Name

Only orderable as a reflex. For more information see 2INHE / Factor II Inhibitor Evaluation, Plasma.

 

Medical Interpretation

Reporting Name

FII Inhib Profile Prof Interp

Specimen Type

Plasma Na Cit

Specimen Stability Information

Specimen Type Temperature Time Special Container
Plasma Na Cit Frozen 14 days

Clinical Information

Coagulation factor inhibitors arise in patients who are congenitally deficient in a specific factor in response to factor replacement therapy or can either occur spontaneously without known cause or in response to a variety of medical conditions, including the postpartum state, immunologic disorders, certain antibiotic therapies, and some malignancies, and in the older adult population.

 

Inhibitors of factor VIII coagulant activity are the most commonly occurring of the specific factor inhibitors.

Reference Values

Only orderable as a reflex. For more information see 2INHE / Factor II Inhibitor Evaluation, Plasma.

 

An interpretive report will be provided.

Interpretation

When no significant abnormalities are detected, a simple descriptive interpretation is provided. When abnormal results are detected, a detailed interpretation is given, including an overview of the results and of their significance, a correlation to available clinical information, and elements of differential diagnosis.

Cautions

No significant cautionary statements

Clinical Reference

1. Hoffman R, Benz Jr EJ, Silberstein LE, et al, eds: Hematology: Basic Principles and Practice. 7th ed. Elsevier; 2018

2. Kasper CK. Treatment of factor VIII inhibitors. Prog Hemost Thromb 1989;9:57-86

3. Kottke-Marchant K, ed. Laboratory Hematology Practice. Wiley Blackwell Publishing; 2012

Method Description

A coagulation expert (clinician or hematopathologist) reviews the laboratory data, and an interpretive report is issued.

Day(s) Performed

Monday through Friday

Report Available

3 to 5 days

Performing Laboratory

Mayo Clinic Laboratories in Rochester

Test Classification

Not Applicable

CPT Code Information

85390-26

LOINC Code Information

Test ID Test Order Name Order LOINC Value
2AINH FII Inhib Profile Prof Interp 69049-5

 

Result ID Test Result Name Result LOINC Value
607489 Reviewed by 18771-6
607445 FII Inhib Profile Prof Interp 69049-5