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HelpTest Code 9INHT Factor IX Inhibitor Profile Technical Interpretation
Specimen Required
Only orderable as part of a profile. For more information see 9INHE / Factor IX Inhibitor Evaluation, Plasma.
Secondary ID
607436Useful For
Technical interpretation of inhibitor to factor IX testing for patients with hemophilia B
Disease States
- Hemophilia B
Method Name
Only orderable as part of a profile. For more information see 9INHE / Factor IX Inhibitor Evaluation, Plasma.
Technical Interpretation
Reporting Name
FIX Inhib Profile Tech InterpSpecimen Type
Plasma Na CitSpecimen Stability Information
| Specimen Type | Temperature | Time | Special Container |
|---|---|---|---|
| Plasma Na Cit | Frozen | 14 days |
Reject Due To
| Gross hemolysis | Reject |
| Gross lipemia | Reject |
| Gross icterus | Reject |
Clinical Information
Factor IX inhibitors arise in patients with severe hemophilia B after factor IX transfusion. Patients with factor IX inhibitors may also develop anaphylactic reactions in response to factor IX infusions. Acquired factor IX inhibitors, occurring in previously healthy people, are exceedingly rare.
Reference Values
Only orderable as part of a profile. For more information see 9INHE / Factor IX Inhibitor Evaluation, Plasma.
An interpretive report will be provided.
Interpretation
When testing is complete, if factor activity results fall within clinically normal ranges, an interpretive comment will be provided noting that inhibitor testing was not indicated and, therefore, not performed. If factor activity indicates the performance of inhibitor screen testing, an interpretive comment will be provided noting the presence or absence of a factor IX inhibitor.
Cautions
Occasionally, a potent lupus-like anticoagulant may cause false-positive testing for a specific factor inhibitor (eg, factor VIII or IX).
Clinical Reference
2. Chitlur M, Warrier I, Rajpurkar M, et al. Inhibitors in factor IX deficiency a report of the ISTH-SSC international FIX inhibitor registry (1997-2006). Haemophilia. 2009;15(5):1027-1031
Method Description
If the factor IX activity level is normal or elevated, a computer-generated interpretive comment indicating inhibitor testing was not indicated and was not performed will be provided.(Unpublished Mayo method)
Day(s) Performed
Monday through Friday
Report Available
3 to 5 daysSpecimen Retention Time
7 daysPerforming Laboratory
Mayo Clinic Laboratories in Rochester
Test Classification
Not ApplicableCPT Code Information
85390
LOINC Code Information
| Test ID | Test Order Name | Order LOINC Value |
|---|---|---|
| 9INHT | FIX Inhib Profile Tech Interp | 69049-5 |
| Result ID | Test Result Name | Result LOINC Value |
|---|---|---|
| 9INHT | FIX Inhib Profile Tech Interp | 69049-5 |