Sign in →

Test Code BILUR Bilirubin, Random, Urine


Shipping Instructions


Ship specimen in amber vial to protect from light.



Specimen Required


Supplies: Sarstedt 5 mL Aliquot Tube (Amber) (T915)

Container/Tube: Amber vial

Specimen Volume: 5 mL

Collection Instructions: Collect a random urine specimen.


Secondary ID

609779

Useful For

Limited use in screening of patients for liver disease

Method Name

Colorimetric

Reporting Name

Bilirubin, Random, U

Specimen Type

Urine

Specimen Minimum Volume

1 mL

Specimen Stability Information

Specimen Type Temperature Time Special Container
Urine Refrigerated (preferred) 7 days LIGHT PROTECTED
  Frozen  90 days LIGHT PROTECTED

Reject Due To

No specimen should be rejected.

Clinical Information

Bilirubin is primarily derived from metabolism of hemoglobin. Only conjugated bilirubin is excreted into the urine and normally only trace amounts can be detected in urine. Elevated urinary bilirubin occurs in patients with obstructive jaundice or jaundice due to hepatocellular disease or injury. However, urine bilirubin is relatively insensitive for detection of liver disease. Hyperbilirubinemia due to hemolysis is principally due to unconjugated bilirubin, and therefore does not result in increased urinary bilirubin.

Reference Values

Negative

Interpretation

Elevated urinary bilirubin is suggestive of hepatocellular disease or post-hepatic biliary obstruction.

Cautions

False positive tests may occur if urine is contaminated with stool, or if the patient is taking drugs which cause red coloration of urine. False negative tests may occur after prolonged storage, exposure to light, or if patient has taken large amounts of ascorbic acid.

Clinical Reference

1. Brunzel NA: Fundamentals of Urine and Body Fluid Analysis. 4th ed. Saunders; 2017

2. Hoilat GJ, John S: Bilirubinuria. In: StatPearls [Internet]. StatPearls Publishing; 2020. Accessed February 12, 2021. Available at www.ncbi.nlm.nih.gov/books/NBK557439/

Method Description

The test is based on the diazotiation reaction coupling of a solid diazonium salt (2,4-dichlorobenzenediazonium tetrachlorozincate) with bilirubin in an acid medium (sulfosalicylic acid) to give the desired reaction.(Package insert: Siemens Ictotest kit, Siemens Healthcare Diagnostics; 10491623 Rev. 09/2017)

Specimen Retention Time

2 Days

Performing Laboratory

Mayo Clinic Laboratories in Rochester

Test Classification

This test has been cleared, approved, or is exempt by the US Food and Drug Administration and is used per manufacturer's instructions. Performance characteristics were verified by Mayo Clinic in a manner consistent with CLIA requirements.

CPT Code Information

81002

LOINC Code Information

Test ID Test Order Name Order LOINC Value
BILUR Bilirubin, Random, U 5770-3

 

Result ID Test Result Name Result LOINC Value
BILUR Bilirubin, Random, U 5770-3

Day(s) Performed

Monday through Sunday

Report Available

Same day/1 day