Test Code FBART Bartonella Antibody Panel, IFA CSF
Specimen Required
Container/Tube: Sterile container
Specimen Volume: 1 mL
Collection Instructions:
1. Submit 1 mL of spinal fluid (CSF).
2. Send refrigerate.
Profile Information
| Test ID | Reporting Name | Available Separately | Always Performed |
|---|---|---|---|
| FBHEN | Bartonella Henselae Ab Panel (CSF) | No | Yes |
| FBARQ | Bartonella Quintana Ab Panel (CSF) | No | Yes |
Method Name
Immunofluorescence Assay (IFA)
Reporting Name
Bartonella Antibody Panel, IFA (CSF)Specimen Type
CSFSpecimen Minimum Volume
0.15 mL
Specimen Stability Information
| Specimen Type | Temperature | Time |
|---|---|---|
| CSF | Refrigerated (preferred) | 14 days |
| Frozen | 30 days | |
| Ambient | 7 days |
Reject Due To
| Gross hemolysis | Reject |
| Gross icterus | Reject |
| Anything other body fluids | Reject |
Reference Values
Bartonella henselae IgG: <1:1
Bartonella henselae IgM: <1:1
Bartonella quintana IgG: <1:1
Bartonella quintana IgM: <1:1
Day(s) Performed
Monday through Saturday
Report Available
3 to 7 daysPerforming Laboratory
Quest DiagnosticsTest Classification
This test was developed and its analytical performance characteristics have been determined by Quest Diagnostics. It has not been cleared or approved by FDA. This assay has been validated pursuant to the CLIA regulations and is used for clinical purposes.CPT Code Information
86611 x 4
LOINC Code Information
| Test ID | Test Order Name | Order LOINC Value |
|---|---|---|
| FBART | Bartonella Antibody Panel, IFA (CSF) | Not Provided |
| Result ID | Test Result Name | Result LOINC Value |
|---|---|---|
| Z0694 | B. Quintana IgG | Not Provided |
| Z0693 | B. Henselae IgG | Not Provided |
| Z0474 | B. Henselae IgM | Not Provided |
| Z0475 | B. Quintana IgM | Not Provided |
Secondary ID
91439Clinical Information
Refer to https://testdirectory.questdiagnostics.com.
Interpretation
Interpretive criteria:
<1:1 Antibody not detected
≥ 1:1 Antibody detected
Infection with Bartonella henselae has been associated with cat scratch disease, bacillary angiomatosis, peliosis hepatis and febrile bacteremia syndrome. Infection with Bartonella quintana has been associated with trench fever and bacillary angiomatosis in both HIV positive and negative individuals.
IgG cross-reactivity between B henselae and B quintana may occur at any titer; however, the infecting species will typically have the higher IgG titer. Crossreactivity of IgM between the two species is limited and typically is not seen.
Diagnosis of infections of the central nervous system can be accomplished by demonstrating the presence of intrathecally-produced specific antibody. However, interpreting results is complicated by low antibody levels found in CSF, passive transfer of antibody from blood, and contamination via bloody taps.