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HelpTest Code FENDI Endothelin I
Specimen Required
Patient Preparation:
Patient should NOT be on any ACTH, Corticosteroids, or hypertension medications, if possible, for at least 48 hours prior to collection of specimen.
Submit only one of the following:
Specimen Type: Serum
Collection Container/Tube:
Preferred: Red top
Acceptable: Serum gel
Submission Container/Tube: 12x75 mm screw capped vial
Specimen Volume: 3 mL
Collection Instructions:
1. Draw blood in a plain, red-top or serum-gel tube(s).
2. Centrifuge and immediately aliquot 3 mL of serum into a plastic vial.
3. Send frozen.
Specimen Type: Plasma
Collection Container/Tube: Lavender top (EDTA)
Submission Container/Tube: 12x75 mm screw capped vial
Specimen Volume: 3 mL
Collection Instructions:
1. Draw blood in a lavender top (EDTA) tube(s).
2. Centrifuge and immediately aliquot 3 mL plasma into a plastic vial.
3. Send frozen.
Secondary ID
75913Method Name
Direct Enzyme Immunoassay (EIA)
Reporting Name
Endothelin ISpecimen Type
VariesSpecimen Minimum Volume
1 mL
Specimen Stability Information
| Specimen Type | Temperature | Time |
|---|---|---|
| Varies | Frozen (preferred) | 180 days |
| Refrigerated | 7 days |
Reject Due To
| Gross hemolysis | Reject |
| Gross lipemia | Reject |
| Gross icterus | Reject |
Clinical Information
Endothelin I is a 21 amino acid peptide produced primarily by vascular endothelial cells. It is also produced by renal mesangial and epithelial cells. Endothelin I has potent effects on peripheral vascular resistance, renal blood flow and glomerular filtration rate. Endothelin I appears to be a mediator of hypertension and acute renal failure of hemolytic uremic syndrome. Levels of Endothelin I are increased in patients with hemolytic uremic syndrome with hypertension anuria and oligonuria. Endothelin I has potent vasoconstriction properties. Endothelin I stimulates the oppositive vasodilator called Endothelium Derived Releasing Factor. Levels are also increased in trauma patients.
Reference Values
Adult Reference Range(s)
4.0-9.0 pg/mL
Day(s) Performed
Monday through Friday
Report Available
12 to 16 daysPerforming Laboratory
Inter Science InstituteTest Classification
This test has not been cleared or approved by the US Food and Drug Administration. This test was developed and its performance characteristics determined by Inter Science Institute. Values obtained with different methods, laboratories, or kits cannot be used interchangeably with the results on this report. The results cannot be interpreted as absolute evidence of the presence or absence of malignant disease.CPT Code Information
83520
LOINC Code Information
| Test ID | Test Order Name | Order LOINC Value |
|---|---|---|
| FENDI | Endothelin I | Not Provided |
| Result ID | Test Result Name | Result LOINC Value |
|---|---|---|
| FENDI | Endothelin I | 49867-5 |