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Test Code FENDI Endothelin I


Specimen Required


Patient Preparation:

Patient should NOT be on any ACTH, Corticosteroids, or hypertension medications, if possible, for at least 48 hours prior to collection of specimen.

 

Submit only one of the following:

 

Specimen Type: Serum

Collection Container/Tube: Red or SST

Submission Container/Tube: 12x75 mm screw capped vial

Specimen Volume: 3 mL

Collection Instructions:

1. Draw blood in a plain, red-top or serum-gel tube(s).

2. Centrifuge immediately.

3. Send 3 mL of serum frozen in a plastic vial.

 

Specimen Type: Plasma

Collection Container/Tube: EDTA

Submission Container/Tube: 12x75 mm screw capped vial

Specimen Volume: 3 mL

Collection Instructions:

1. Draw blood in a lavender top (EDTA) tube(s).

2. Centrifuge immediately.

3. Send 3 mL of plasma frozen in a plastic vial.


Secondary ID

75913

Method Name

Direct RIA

Reporting Name

Endothelin I

Specimen Type

Varies

Specimen Minimum Volume

1 mL

Specimen Stability Information

Specimen Type Temperature Time Special Container
Varies Frozen (preferred) 180 days
  Refrigerated  7 days

Reject Due To

Gross hemolysis Reject
Gross lipemia Reject
Gross icterus Reject

Clinical Information

Endothelin I is a 21 amino acid peptide produced primarily by vascular endothelial cells. It is also produced by renal mesangial and epithelial cells. Endothelin I has potent effects on peripheral vascular resistance, renal blood flow and glomerular filtration rate. Endothelin I appears to be a mediator of hypertension and acute renal failure of hemolytic uremic syndrome. Levels of Endothelin I are increased in patients with hemolytic uremic syndrome with hypertension anuria and oligonuria. Endothelin I has potent vasoconstriction properties. Endothelin I stimulates the oppositive vasodilator called Endothelium Derived Releasing Factor. Levels are also increased in trauma patients.

Reference Values

Adult Reference Range(s)

4.0-9.0 pg/mL

Day(s) Performed

Monday through Friday

Report Available

12 to 16 days

Performing Laboratory

Inter Science Institute

Test Classification

This test was developed and its performance characteristics determined by Inter Science Institute. Values obtained with different methods, laboratories, or kits cannot be used interchangeably with the results on this report. The results cannot be interpreted as absolute evidence of the presences or absence of malignant disease.

CPT Code Information

83519

 

LOINC Code Information

Test ID Test Order Name Order LOINC Value
FENDI Endothelin I Not Provided

 

Result ID Test Result Name Result LOINC Value
FENDI Endothelin I 49867-5