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HelpTest Code FROS2 Fructose, Qualitative, Semen
Specimen Required
Patient Preparation: Patient should have 2 to 7 days of sexual abstinence at the time of semen collection.
Submit only 1 of the following specimens:
Specimen Type: Semen
Collection Container/Tube: Sterile container
Submission Container/Tube: Plastic container
Specimen Volume: Total ejaculate
Collection Instructions: Do not dilute specimen. Freeze specimen at -20° C.
Specimen Type: Seminal plasma
Container/Tube: Plastic vial
Specimen Volume: 0.5 mL
Collection Instructions:
1. After semen collection, wait 30 to 40 minutes until the semen is liquefied, then centrifuge the semen for 10 minutes at maximum centrifuge speed.
2. Remove top 3/4 of specimen with a pipet and place in a plastic vial. Freeze specimen at -20° C.
3. Discard remainder of centrifuged specimen.
Secondary ID
92187Useful For
Establishing the origin of azoospermia in patients with azoospermia and low volume ejaculates
Method Name
Qualitative
Reporting Name
Qualitative Fructose,SemenSpecimen Type
SemenSpecimen Minimum Volume
0.5 mL
Specimen Stability Information
| Specimen Type | Temperature | Time | Special Container |
|---|---|---|---|
| Semen | Frozen | ||
Reject Due To
All specimens will be evaluated at Mayo Clinic Laboratories for test suitability.Clinical Information
Fructose is produced in the male reproductive tract by the seminal vesicles and is released into the semen during ejaculation. Fructose is the energy source for sperm motility.
Reference Values
Positive
Interpretation
A positive (indicated by color change) fructose is considered normal.
A semen specimen that contains no sperm (azoospermia) and is fructose negative may indicate an absence of the seminal vesicles, absence of the vas deferens in the area of the seminal vesicles, or an obstruction at the level of the seminal vesicles.
Cautions
This test should be performed in conjunction with a semen analysis to determine semen volume, pH, sperm concentration, motility, and grade of forward progression.
Fructose test must be on a separate ejaculate.
Clinical Reference
1. Lipshultz LI, Howards SS, Niederberger CS, eds: In: Infertility in the Male. 4th ed. Cambridge University Press 2009
2. Risz B, Agarwal A, Sabanegh ES, eds: Male Infertility in Reproductive Medicine: Diagnosis and Management. CRC Press; 2019
Method Description
A qualitative method using resorcinol will detect the presence or absence of fructose.(Keel BA, Webster BW: Handbook of the Laboratory Diagnosis and Treatment of Infertility. CRC Press: 1990:49)
Day(s) Performed
Friday
Report Available
1 to 7 daysSpecimen Retention Time
Not retainedPerforming Laboratory
Mayo Clinic Laboratories in Rochester
Test Classification
This test was developed and its performance characteristics determined by Mayo Clinic in a manner consistent with CLIA requirements. It has not been cleared or approved by the US Food and Drug Administration.CPT Code Information
82757
LOINC Code Information
| Test ID | Test Order Name | Order LOINC Value |
|---|---|---|
| FROS2 | Qualitative Fructose,Semen | 13943-6 |
| Result ID | Test Result Name | Result LOINC Value |
|---|---|---|
| FRUCS | Fructose, Semen/Seminal P | 13943-6 |
| CLSM | Collection Site | 56816-2 |
| VOLSM | Semen Volume | 3160-9 |
| CMT49 | Comment | 48767-8 |