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Test Code LAB4056 CREATINE KINASE

Specimen Type

Preferred Sample: Lithium Heparin Tube (Mint Green Top, Dark Green Top)
Alternative Sample: Serum (SST, Gold, Corvac, Tiger, Red Top Tube)

 

Specimen Volume

1 mL

Minimum Volume

0.5 mL

Turnaround Time

STAT: 1 hour
Routine: 4 hours

Test Schedule

Daily

Sample Stability

Room Temp: 2 days
Refrigerated: 7 days

Method

Colorimetric

Reference Ranges

Age Sex Range
0 up to 30 days Female 145 - 1,578 U/L
30 days up to 19 years Female 30 - 240 U/L
19 years and older Female 29 - 168 U/L
0 up to 30 days Male 145 - 1578 U/L
30 days up to 19 years Male 55 - 400 U/L
19 years and older Male 30 - 200 U/L

 

Reporting Limit

Measuring Range 7 - 4267 U/L

Reporting Limits 7 – 42,670 U/L

Synonyms

CPK; CK Total; Creatine Phosphokinase;

CPT Codes

82550

Test Components

CK, U/L

LOINC Code

2157-6

IMO Code

IMO-PROC-30995234

Clinical Information

Creatine Kinase (CK) is an enzyme that mainly exists in the heart, skeletal muscles and a small amount in the brain. When cells of the heart, muscles or brain become damaged, they release creatine kinase into the blood stream. Any condition, injury or event that causes muscle damage or interferes with muscle energy production will increase levels of CK in the blood, e.g., intense exercise or muscle diseases (myopathies) such as muscular dystrophy.

 

Creatine kinase can also be elevated in certain conditions that aren’t directly related to muscles such as thyroid disease, infections, kidney failure, and connective tissue disorders. Since creatine kinase levels increase when muscle is damaged it can be used in the diagnosis and treatment of diseases associated with skeletal muscle, heart, central nervous system, and thyroid.