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Test Code LAB4066 CREATININE CLEARANCE

Important Note

No Blood Creatinine collection will be requested for patients that have had a Blood Creatinine result in the past two days.

Patients Height, Weight, Collection Period of urine and Total Volume of urine are necessary for calcutation of results. Refer to 24 hour urine collection procedure for instructions.

 

Specimen Type

24 hour urine collection.

Preferred Specimen: Lithium Heparin Plasma (Mint Green Top, Dark Green Top)
Alternative Specimen: Serum (SST, Gold, Corvac, Tiger, Red Top Tube)

 

Collection Instructions

Collect a 24-hour urine in a 24-hour dark plastic urine container. Refrigerate during collection. Collect a serum creatinine level within 48 hours of urine creatinine being analyzed.

Specimen Volume

2 mL plasma/serum and 50 mL urine

Minimum Volume

0.5mL plasma/serum and 2 mL urine

Turnaround Time

STAT: 1 hour
Routine: 4 hours

Test Schedule

Daily

Specimen Processing

Invert 24 hour urine container several times to mix the specimen.
Aliquot 50 mL of a well-mixed 24-hour urine collection into a leakproof plastic urine container.
Aliquot 5 mL into a transparent red top tube.
Record collection time and total volume.
Freeze 50ml Specimen Aliquot.

Method

Enzymatic

Reference Ranges

Serum Creatinine: mg/dL

       0 to 28 Days: 0.3 - 1.0 mg/dL

       29 Days to 1 Year: 0.2 - 0.4 mg/dL

       1 to 11 Years:  0.3 - 0.7 mg/dL

       12 to 18 Years: 0.5 - 1.0 mg/dL

       > 18 years: Male: 0.5 - 1.3 mg/dL

       > 18 years: Female: 0.4 - 1.0 mg/dL         

Urine Creatinine,

         Male: 1.0-2.4 g/24h

         Female:  0.7-1.6 g/24h

Creatinine Clearance mL/min

  0-2 yrs

    Male: 51-73

    Female:  51-73

  2-10 yrs

    Male:  64-92

    Female: 64-92

  10-12 yrs

    Male:  83-119

    Female:  83-119

  12-40 yrs

    Male:  97-137

    Female:  88-128

  40-50 yrs

    Male:  91-131

    Female:  82-122

  50-60 yrs

    Male:  85-125

    Female:  76-116

  60-70 yrs

    Male: 79-119

    Female: 70-110

  70-80 yrs

    Male: 73-113

    Female:  64-104

  80+ yrs

    Male:  67-107

    Female: 58-98

Test Components

Height, in; Weight, lbs,Time, h; Volume, mL; Creatinine, mg/dL; Creatinine, Urine, g/24hr; Creatinine Clearance, mL/min.

CPT Codes

82575