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Test Code LAB4077 DIGOXIN (LANOXIN) 

Specimen Type

Preferred Sample: Lithium Heparin Plasma ( Mint Green Tube or Dark Green)
Alternative Sample: Serum (SST, Gold, Corvac, Tiger, Red Top Tube)

Collection Instructions

Draw just prior to next dose. Note time of dose and drawing.

Specimen Volume

1 mL

Minimum Volume

0.5 mL

Turnaround Time

STAT: 1 hour 
Routine: 4 hours

Test Schedule

Daily

Sample Stability

Refrigerated: 48 hours
Frozen: 7 days

Method

Colorimetric

Reference Ranges

Digoxin, ng/mL

    Therapeutic:   0.8-2.0

    Toxic:           Greater than 2.0

Increased risk of Digoxin toxicity at levels greater than 2.0 ng/mL, with a wide zone of concentrations that may be toxic in one individual and not in another. The risk is greater with CHD and with decreases in Potassium, Calcium and Magnesium. Digoxin destribution phase complete after 8-15 hours.

Reporting Limit

Measuring Range 0.19 – 5.00 ng/mL 

Reporting Limits 0.19 – 40.0 ng/mL

Synonyms

Lanoxin, Acylanid, Cedilanid, Cedilanid-D, Davoxin, Deslanoslide, Lantoslide C and Seroxin.

Test Components

Digoxin, ng/mL

CPT Codes

80162

 

Limitations

Studies have shown that therapeutic drug levles may be altered in serum/plasma that remains in contact with separator gel. Therapeutic drug levels collected in an SST or PST should be run within 24 hours of collection.