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Test Code LAB4091 FIBRINOGEN

Important Note

Blue Sodium Citrate tube must be filled completely to maintin correct anticoagulant / blood ratio.

Specimen Type

Blue top tube (buffered sodium citrate)

Specimen Volume

3mL Blue top (3.2% Sodium Citrate), or

5mL Blue top (3.2% Sodium Citrate), or

1mL Blue top (3.2% Sodium Citrate) MiniCollect vial, or

500uL (minimum) Sodium Citrate Plasma spun and removed from cells.

Minimum Volume

0.5 mL Plasma from properly filled Sodium Citrate (Blue top) tube, or

1mL Blue top (Sodium Citrate) MiniCollect vial.

Turnaround Time

STAT: 1 hour
Routine: 4 hours

Test Schedule

Daily

Sample Stability

Room Temp: 8 hours, spun or unspun

Frozen samples are stable for 2 weeks at -20C or 12 months at -70C.

Method

Electromechanical

Reference Ranges

Fibrinogen: 212.0 – 451.0 mg/dL

CPT Codes

85384

Test Components

Fibrinogen, mg/dL.

Test Limitations

Blood/anticoagulant volume is critical.

Clinical Information

The Fibrinogen test is used to measure the amount of fibrinogen in a sample. The concentration of fibrinogen is inversely proportional to the clotting time when a known amount of thrombin (in excess) is added to dilute patient plasma. Low functional fibrinogen levels may be seen in DIC, during massive bleeding, liver disease, fibrinolysis, thrombolytic therapy, in the rare congenitally deficient patient (afibrinogenemia), or patients with nonfunctional fibrinogen protein. Elevated fibrinogen levels can be observed in diabetes, inflammatory syndromes, or obesity, and may be associated with an increased risk of cardiovascular disease and pre-thrombolytic states.