Test Code LAB4105 FRACTIONAL EXCRETION OF SODIUM
Specimen Type
BLOOD
Preferred Sample: Lithium Heparin Plasma (Mint Green Top, Dark Green Top)
Alternative Sample: Serum (SST, Gold, Corvac, Tiger, Red Top Tube)
URINE
Preferred Specimen: Transparent Red Top Tube
Alternative Specimen: Yellow Urine Tube, Sterile Container
Specimen Volume
2 mL Plasma/Serum
10 mL Urine
Minimum Volume
1 mL Plasma/Serum
5 mL Urine
Turnaround Time
STAT: 1 hour
Routine: 4 hours
Test Schedule
Daily
Sample Stability
Room Temp: 14 days
Refrigerated: 14 days
Method
ISE (Ion Selective Electrode), Calculation
Reference Ranges
Prerenal Intrinsic Renal Postrenal Ur Sodium < 20 > 40 > 40 FENa < 1% > 1% > 4% Prerenal: Anything that causes decreased effective renal perfusion: Hypovolemia, CHF, Renal Artery Stenosis, Sepsis, etc. Remember, contrast-induced nephropathy will often look pre-renal Intrinsic Renal: ATN, AIN, Glomerulohephritides, etc Postrenal: Obstruction (BPH, bladder stone, bilateral ureter obstruction)
CPT Codes
82565, 82570, 84295, 84300
Test Components
Sodium, Creatinine, Random Urine Sodium, Random Urine Creatinine, Fractional Excretion of Sodium
Collection Instructions
Both plasma and random urine should be obtained