Test Code LAB4164 PLATELET FUNCTION TEST
New Method Comparison
Below is a brief summary of the reporting with the new TEG method:
|
Parameter |
Clinical Usage |
Interpretation |
PFA-100 equivalent |
|
|
ADP |
Therapy response for patients taking P2Y12 / ADP inhibitors (e.g., clopidogrel, prasugrel, ticagrelor) |
Stronger inhibition = lower MA (i.e., flags low) |
Weaker inhibition = higher MA (i.e., flags normal or high) |
Collagen/ADP |
|
AA |
Therapy response for patients taking Arachidonic Acid inhibitors (e.g., aspirin) |
Stronger inhibition = lower MA (i.e., flags low) |
Weaker inhibition = higher MA (i.e., flags normal or high) |
Collagen/Epi |
|
HKH |
Evaluates underlying hemostasis to determine maximum and minimum platelet function |
Baseline underlying clot strength; thrombin activated; maximum platelet function |
Less inhibition will see the ADP/AA result closer to the baseline (i.e., HKH) |
Platelet count and hematocrit |
|
ActF |
Isolates platelet contribution; fibrin only result; minimum platelet function |
Increasing inhibition will see the ADP/AA result move closer to the fibrin only result (i.e., ActF) |
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