Test Code LAB7075 Tree Nuts Profile
Additional Codes
Mayo ID: PR288 (custom panel)
LabCorp: 671926
Specimen Type and Requirments
Supplies: Sarstedt Aliquot Tube, 5 mL (T914)
Collection Container/Tube:
Preferred: Serum gel
Acceptable: Red top
Submission Container/Tube: Plastic vial
Specimen Volume: 1.8 mL
Collection Instructions: Centrifuge and aliquot serum into a plastic vial.
Specimen Rejection Criteria
| Gross hemolysis | OK |
| Gross lipemia | OK |
Sample Stability
Refrigerated (prefered) - 14 days
Frozen - 90 days
Profile Information
| Test ID | Reporting Name | Available Separately | Always Performed | Test Component Link |
|---|---|---|---|---|
|
ALM |
Almond, IgE | Yes | Yes | Almond, IgE, Serum - Kootenai Health |
|
BRAZ |
Brazil Nut, IgE | Yes | Yes | Brazil Nut, IgE, Serum - Kootenai Health |
|
CASH |
Cashew, IgE | Yes | Yes | Cashew, IgE, Serum - Kootenai Health |
|
CNUT |
Chestnut, Sweet, IgE | Yes | Yes | Chestnut, Sweet, IgE, Serum - Kootenai Health |
|
NUTH |
Hazelnut-Food, IgE | Yes | Yes | Hazelnut-Food, IgE, Serum - Kootenai Health |
|
PEC |
Pecan-Food, IgE | Yes | Yes | Pecan-Food, IgE, Serum - Kootenai Health |
| PINE | Pine Nut, IgE | Yes | Yes | Pine Nut, IgE, Serum - Kootenai Health |
|
PISTA |
Pistachio, IgE | Yes | Yes | Pistachio, IgE, Serum - Kootenai Health |
|
BLW |
Walnut-Food, IgE | Yes | Yes | Walnut-Food, IgE, Serum - Kootenai Health |
| CCNT | Coconut, IgE | Yes | Yes | Coconut, IgE, Serum - Kootenai Health |
Method
Fluorescence Enzyme Immunoassay (FEIA)
Reference Ranges
|
Class |
IgE kU/L |
Interpretation |
|
0 |
<0.10 |
Negative |
|
0/1 |
0.10-0.34 |
Borderline/Equivocal |
|
1 |
0.35-0.69 |
Equivocal |
|
2 |
0.70-3.49 |
Positive |
|
3 |
3.50-17.4 |
Positive |
|
4 |
17.5-49.9 |
Strongly positive |
|
5 |
50.0-99.9 |
Strongly positive |
|
6 |
≥100 |
Strongly positive |
Concentrations of 0.70 kU/L or more (class 2 and above) will flag as abnormally high.
Reference values apply to all ages.
CPT Code
86003x10
Special Instructions
https://www.mayocliniclabs.com/it-mmfiles/Allergens-IgE_Antibodies.pdf
LOINC Code Information
| Test ID | Test Name | LOINC |
| ALM | Almond, IgE | 6019-4 |
| BRAZ | Brazil Nut, IgE | 6050-9 |
| CASH | Cashew, IgE | 6718-1 |
| CNUT | Chestnut, Sweet, IgE | 6259-6 |
| NUTH | Hazelnut-Food, IgE | 6136-6 |
| PEC | Pecan-Food, IgE | 6208-3 |
| PINE | Pine Nut, IgE | 10954-6 |
| PISTA | Pistachio, IgE | 7613-3 |
| BLW | Walnut-Food, IgE | 6273-7 |
| CCNT | Coconut, IgE | 6081-4 |
Report Available
Same day/1 to 3 days
Specimen Retention Time
14 days
Interpretation
Detection of IgE antibodies in serum (class 1 or greater) indicates an increased likelihood of allergic disease as opposed to other etiologies and defines the allergens responsible for eliciting signs and symptoms.
The level of IgE antibodies in serum varies directly with the concentration of IgE antibodies expressed as a class score or kU/L.
Clinical Information
Establishing a diagnosis of an allergy to tree nuts (almond, brazil nut, cashew, chestnut, hazelnut, pecan, pine nut, pistachio, walnut, coconut)
Defining the allergen responsible for eliciting signs and symptoms
Identifying allergens:
-Responsible for allergic response and/or anaphylactic episode
-To confirm sensitization prior to beginning immunotherapy
-To investigate the specificity of allergic reactions to insect venom allergens, drugs, or chemical allergens
Testing for IgE antibodies is not useful in patients previously treated with immunotherapy to determine if residual clinical sensitivity exists or in patients in whom the medical management does not depend upon identification of allergen specificity.