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Immunofixation and Protein Electrophoresis (Blood or Urine) Ordering Guide

Important Note

Kootenai Health utilizes Mayo Clinic Laboratories for analyzing monoclonal proteins. Mayo clinic uses mass spectrometry methodology for this testing, and their recommended diagnostic testing algorithms for Multiple Myeloma and Amyloidosis are located below: 

Multiple Myeloma: Laboratory Screening

Amyloidosis: Laboratory Approach to Diagnosis

Requests for "immunofixation" or "IFE" and "electrophoresis" or "SPEP" tests are referring to other methods of monoclonal protein testing utilized at specific laboratories. These are different methods but results are used in the same manner. 

For KH Lab locations receiving these orders, please order the following: 

**Do not need separate Albumin order if CMP, Renal, or Hepatic panel also ordered
***Immunoglobulin panel (IgA, IgG, IgM) is included in the QMPSS test and does not need to be ordered separately if requested.

Please reach out to KH Lab leadership with any further questions if unsure what to order. 

Additional Codes

 

LabCorp Test

Mayo Clinic Test

001685 – Immunofixation (IFE), serum

LAB4655 – QMPSS Monoclonal Protein Study, Quantitative, Serum

 

LAB5214 – FLCS Immunoglobulin Free Light Chains, Serum

 

001487 – Protein Electrophoresis, serum

LAB4655 – QMPSS Monoclonal Protein Study, Quantitative, Serum

 

LAB4006 – Albumin *Do not order if CMP, Renal, or Hepatic panel also ordered*

 

001495 – Immunofixation (IFE), Serum and Protein Electrophoresis, Serum

 

120256 – Immunofixation (IFE), Serum, Protein Electrophoresis (PE), Serum, and Quantitative Free κ and λ Light Chains (FLC) Plus Ratio, Serum

 

123055 – Protein Electrophoresis with Interpretation, Serum with Reflex to IFE, Serum, and Free κ and λ Light Chains, Serum

 

123100 - Protein Electrophoresis, Serum with Reflex to IFE, Serum

 

123026 - Protein Electrophoresis with Interpretation, Serum with Reflex to IFE, Serum

 

LAB4655 – QMPSS Monoclonal Protein Study, Quantitative, Serum

 

LAB5214 – FLCS Immunoglobulin Free Light Chains, Serum

 

LAB4006 – Albumin *Do not order if CMP, Renal, or hepatic panel also ordered*

123034 – Immunofixation (IFE), Urine

*Ordering provider will need to specify 24-hour or random*

 

LAB5455 – MPU Monoclonal Protein Studies, 24 Hour, Urine

 

or

 

LAB5247 – RMPU Monoclonal Protein Studies, Random, Urine

 

122390 – Immunofixation (IFE) and Protein Electrophoresis, Random Urine

 

003715 – Protein Electrophoresis, Random Urine with Reflex to IFE, Random Urine

 

354928 – Protein Electrophoresis, Random Urine

 

LAB5247 – RMPU Monoclonal Protein Studies, Random, Urine

003467 – Immunofixation (IFE) and Protein Electrophoresis, 24-Hour Urine

 

123018 – Protein Electrophoresis with Interpretation, 24-Hour Urine with Reflex to IFE, 24-Hour Urine

 

003368 – Protein Electrophoresis, 24-Hour Urine

LAB5455 – MPU Monoclonal Protein Studies, 24 Hour, Urine

 

Quest Diagnostics Test

Mayo Clinic Test

549 – Immunofixation, serum

 

37669 – Immunofixation (IFE) and Immunoglobulins Panel (IgG, IgA, IgM), Serum

 

LAB4655 – QMPSS Monoclonal Protein Study, Quantitative, Serum

 

LAB5214 – FLCS Immunoglobulin Free Light Chains, Serum

 

213 – Immunofixation, Urine

*Ordering provider will need to specify 24-hour or random*

 

 

LAB5455 – MPU Monoclonal Protein Studies, 24 Hour, Urine

or

LAB5247 – RMPU Monoclonal Protein Studies, Random, Urine

24629 – Protein, Total and Protein Electrophoresis with Immunofixation (IFE), Serum

 

LAB4655 – QMPSS Monoclonal Protein Study, Quantitative, Serum

 

LAB5214 – FLCS Immunoglobulin Free Light Chains, Serum

 

LAB4006 – Albumin *Do not order if CMP, Renal, or hepatic panel also ordered*

38944 – Protein, Total and Protein Electrophoresis, 24 Hour Urine and Immunofixation

 

LAB5455 – Monoclonal Protein Studies, 24 Hour, Urine

 

8525 – Protein Electrophoresis and Total Protein, Random Urine

 

LAB5247 – Monoclonal Protein Studies, Random, Urine

15122 – Kappa/Lambda Light Chains, Free with Ratio and Reflex to Immunofixation

 

LAB5214 – FLCS Immunoglobulin Free Light Chains, Serum