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HelpTest Code TRIGC Triglycerides, CDC, Serum
Reporting Name
Triglycerides, CDC, SPerforming Laboratory
Mayo Clinic Laboratories in Rochester
Specimen Type
SerumSpecimen Required
Only orderable as part of a profile. For more information see LMPP / Lipoprotein Metabolism Profile, Serum.
Patient Preparation:
1. Fasting-overnight (12-14 hours)
2. Patient must not consume any alcohol for 24 hours before the specimen is collected.
Collection Container/Tube:
Preferred: Serum gel
Acceptable: Red top
Submission Container/Tube: Plastic vial
Specimen Volume: 5 mL
Collection Instructions: Centrifuge and aliquot serum into a plastic vial.
Specimen Minimum Volume
0.25 mL
Specimen Stability Information
| Specimen Type | Temperature | Time | Special Container |
|---|---|---|---|
| Serum | Refrigerated (preferred) | 7 days | |
| Frozen | 60 days |
Test Classification
This test has been cleared, approved, or is exempt by the US Food and Drug Administration and is used per manufacturer's instructions. Performance characteristics were verified by Mayo Clinic in a manner consistent with CLIA requirements.LOINC Code Information
| Test ID | Test Order Name | Order LOINC Value |
|---|---|---|
| TRIGC | Triglycerides, CDC, S | 2571-8 |
| Result ID | Test Result Name | Result LOINC Value |
|---|---|---|
| TRIGC | Triglycerides, CDC, S | 2571-8 |
Reference Values
Only orderable as part of a profile. For more information see LMPP / Lipoprotein Metabolism Profile, Serum.
Triglycerides
2-9 years:
Acceptable: <75 mg/dL
Borderline high: 75-99 mg/dL
High: ≥100 mg/dL
10-17 years:
Acceptable: <90 mg/dL
Borderline high: 90-129 mg/dL
High: ≥130 mg/dL
≥18 years:
Normal: <150 mg/dL
Borderline high: 150-199 mg/dL
High: 200-499 mg/dL
Very high: ≥500 mg/dL
Reference values have not been established for patients who are less than 2 years of age.
CPT Code Information
84478
Method Name
Only orderable as part of a profile. For more information see LMPP / Lipoprotein Metabolism Profile, Serum.
Enzymatic Colorimetric
Secondary ID
606879Useful For
Measurement of triglyceride as a part of lipoprotein profiling
Reject Due To
| Gross hemolysis | Reject |
Clinical Information
Triglycerides are esters of the trihydric alcohol, glycerol, with 3 long-chain fatty acids. They are partly synthesized in the liver and partly derived from the diet.
Interpretation
Increased plasma triglyceride levels are indicative of a metabolic abnormality and, along with elevated cholesterol, are considered a risk factor for atherosclerotic disease. Hyperlipidemia may be inherited or be associated with biliary obstruction, diabetes mellitus, nephrotic syndrome, renal failure, or metabolic disorders related to endocrinopathies. Increased triglycerides may also be associated with alcohol consumption, sedentarism or medication-induced (eg, prednisone).
Since cholesterol and triglycerides can vary independently, measurement of both is more meaningful than the measurement of cholesterol only.
Cautions
Triglyceride result can be falsely decreased in patients with elevated levels of N-acetyl-p-benzoquinone imine (NAPQI)-a metabolite of acetaminophen, N-acetylcysteine (NAC), and metamizole.
Clinical Reference
1. Grundy SM, Stone NJ, Bailey AL, et al: 2018 AHA/ACC/AACVPR/AAPA/ABC/ACPM/ADA/AGS/APhA/ASPC/NLA/PCNA Guideline on the Management of Blood Cholesterol: A Report of the American College of Cardiology/American Heart Association Task Force on Clinical Practice Guidelines. Circulation. 2019 Jun 18;139(25):e1082-e1143. doi: 10.1016/j.jacc.2018.11.002.
2. Expert Panel on Integrated Guidelines for Cardiovascular Health and Risk Reduction in Children and Adolescents; National Heart, Lung, and Blood Institute: Expert panel on integrated guidelines for cardiovascular health and risk reduction in children and adolescents: summary report. Pediatrics. 2011 Dec;128 Suppl 5:S213-S256
3. Rosenson RS, Najera SD, Hegele RA: Heterozygous familial hypercholesterolemia presenting as chylomicronemia syndrome. J Clin Lipidol. 2017 Jan - Feb;11(1):294-296. doi: 10.1016/j.jacl.2016.12.005
4. Hopkins PN, Brinton EA, Nanjee MN: Hyperlipoproteinemia type 3: the forgotten phenotype. Curr Atheroscler Rep. 2014 Sep;16(9):440. doi: 10.1007/s11883-014-0440-2
5. Gotoda T, Shirai K, Ohta T, et al: Diagnosis and management of type I and type V hyperlipoproteinemia. J Atheroscler Thromb. 2012;19(1):1-12
6. Gonzales KM, Donato LJ, Shah P, Simha V: Measurement of apolipoprotein B levels helps in the identification of patients at risk for hypertriglyceridemic pancreatitis. J Clin Lipidol. 2021 Jan-Feb;15(1):97-103. doi: 10.1016/j.jacl.2020.11.010
Method Description
Samples analyzed for triglycerides are measured by an automated enzymatic method. The chemistry includes hydrolysis of the triglycerides and phosphorylation of the resulting glycerol.(Package insert: Roche Triglycerides Reagent. Roche Diagnostics; V12.0, 11/2017)
Day(s) Performed
Monday through Thursday, Sunday